\n
\n Bio
\n
“Resting State fMRI in Epilepsy for Seizure Onset Localizatio
n: Evidence and Methods”
\n
\n
Varina L. Boerwinkle\, MD is the Division Chief
of Child Neurology at the University of North Carolina in Chapel Hill\, a
nd Professor of Neurology. She is also the medical director of the Functio
nal Neuroimaging and Neuroscience Laboratory and Pediatric Neurocritical C
are Service. She earned her medical degree from University of Texas Southw
estern and completed a residency in child neurology at Baylor College of M
edicine.
\n
Her clinical and research efforts in brain networks began
in 2010. She pioneered the clinical utilization of resting state function
al MRI (rs-fMRI) for children to localize seizure onset zones\, and brain
networks\, and improve epilepsy surgery outcomes. Through her efforts\, ov
er 2000 individual children primarily with epilepsy have received rs-fMRI
with clinically impactful results. For many of these children\, who are un
able to perform demanding tests reliably\, rs-fMRI\, analyzed by methods v
alidated in her lab\, offers comprehensive major brain network characteriz
ation with the capacity for clinical correlation.
\n
\n
▶RECORDING
\n
\n
\n
Abstract
\n
\n
\n
“Resting State fMRI in Epilepsy f
or Seizure Onset Localization: Evidence and Methods”
\n
\n
\n
Epilepsy effects over 50 million worldwide
and the only known cure is surgery. However\, the success of the surgery r
elies on accurate localization of the seizure onset zone\, which with stan
dard techniques ranges 30-70%. Recently\, resting state fMRI has been show
n to not only show the normal networks to avoid surgical morbidity\, but t
o also localize the seizure network. In this presentation we will review t
he evidence behind this new diagnostic and discuss potential avenue for fu
ture investigations. .
\n
\n
▶RECORDING
\n
\n