Murray B. Sachs Professor of Biomedical Engineering
Center for Cardiovascular Bioinformatics and Modeling
3400 N. Charles Street
Hackerman Hall, Room 216
Baltimore, MD 21218
Phone: (410) 516-4375
Fax: (410) 516-5294
E-mail: ntrayanova | at | jhu.edu
The mission of Dr. Trayanova's Computational Cardiac Electrophysiology Laboratory is to conduct research, by developing cutting-edge computational tools and simulation-experiment approaches, to advance the understanding of the fundamental mechanisms that underly rhythm disorders in the heart and to uncover better strategies for prevention and treatment of these disorders.
Wright P. T., V. O. Nikolaev, T. O'Hara, I. Diakonov, A. Bhargava, S. Tokar, S. Schobesberger, A. I. Shevchuk, M. B. Sikkel, R. Wilkinson, N. A. Trayanova, A. R. Lyon, S. E. Harding and J. Gorelik (2014). "Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling." J Mol Cell Cardiol, 67: 38-48.
Zhou L., S. Solhjoo, B. Millare, G. Plank, M. R. Abraham, S. Cortassa, N. Trayanova and B. O'Rourke (2014). "Effects of regional mitochondrial depolarization on electrical propagation: implications for arrhythmogenesis." Circ Arrhythm Electrophysiol, 7(1): 143-51.
Trayanova N. A. and L. J. Rantner (2014). "New insights into defibrillation of the heart from realistic simulation studies." Europace, 16(5): 705-13.
Yuxuan H., V. Gurev, J. Constantino and N. Trayanova (2014). "Optimizing CRT to Minimize ATP Consumption Heterogeneity Throughout the Left Ventricle: A Simulation Analysis Using a Canine Heart Failure Model." Heart Rhythm.
Trayanova N. A. (2014). "Virtual 3D heart models to aid pacemaker implantation in children." Future Cardiol, 10(1): 5-8.