Murray B. Sachs Professor of Biomedical Engineering
Center for Cardiovascular Bioinformatics and Modeling
3400 N. Charles Street
Hackerman Hall, Room 216
Baltimore, MD 21218
Phone: (410) 516-4375
Fax: (410) 516-5294
E-mail: ntrayanova | at | jhu.edu
The mission of Dr. Trayanova's Computational Cardiac Electrophysiology Laboratory is to conduct research, by developing cutting-edge computational tools and simulation-experiment approaches, to advance the understanding of the fundamental mechanisms that underly rhythm disorders in the heart and to uncover better strategies for prevention and treatment of these disorders.
Boyle P.M., T.V. Karathanos and N.A. Trayanova (2014). "â€œBeauty is a light in the heartâ€: The transformative potential of optogenetics for clinical applications in cardiovascular medicine ." Trends in Cardiovascular Medicine, (ePub ahead of print).
Boyle P. M., E. Entcheva and N. A. Trayanova (2014). "See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?." Expert Rev Cardiovasc Ther, 12(1): 17-20.
Wright P. T., V. O. Nikolaev, T. O'Hara, I. Diakonov, A. Bhargava, S. Tokar, S. Schobesberger, A. I. Shevchuk, M. B. Sikkel, R. Wilkinson, N. A. Trayanova, A. R. Lyon, S. E. Harding and J. Gorelik (2014). "Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling." J Mol Cell Cardiol, 67: 38-48.
Zhou L., S. Solhjoo, B. Millare, G. Plank, M. R. Abraham, S. Cortassa, N. Trayanova and B. O'Rourke (2014). "Effects of regional mitochondrial depolarization on electrical propagation: implications for arrhythmogenesis." Circ Arrhythm Electrophysiol, 7(1): 143-51.
Trayanova N. A. and L. J. Rantner (2014). "New insights into defibrillation of the heart from realistic simulation studies." Europace, 16(5): 705-13.