Murray B. Sachs Professor of Biomedical Engineering
Center for Cardiovascular Bioinformatics and Modeling
3400 N. Charles Street
Hackerman Hall, Room 216
Baltimore, MD 21218
Phone: (410) 516-4375
Fax: (410) 516-5294
E-mail: ntrayanova | at | jhu.edu
The mission of Dr. Trayanova's Computational Cardiac Electrophysiology Laboratory is to conduct research, by developing cutting-edge computational tools and simulation-experiment approaches, to advance the understanding of the fundamental mechanisms that underly rhythm disorders in the heart and to uncover better strategies for prevention and treatment of these disorders.
Boyle P. M., C. J. Park, H. J. Arevalo, E. J. Vigmond and N. A. Trayanova (2014). "Sodium current reduction unmasks a structure-dependent substrate for arrhythmogenesis in the normal ventricles." PLoS One, 9(1): e86947.
Yuxuan H., V. Gurev, J. Constantino and N. Trayanova (2014). "Optimizing CRT to Minimize ATP Consumption Heterogeneity Throughout the Left Ventricle: A Simulation Analysis Using a Canine Heart Failure Model." Heart Rhythm.
Boyle P. M., E. Entcheva and N. A. Trayanova (2014). "See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?." Expert Rev Cardiovasc Ther, 12(1): 17-20.
Wright P. T., V. O. Nikolaev, T. O'Hara, I. Diakonov, A. Bhargava, S. Tokar, S. Schobesberger, A. I. Shevchuk, M. B. Sikkel, R. Wilkinson, N. A. Trayanova, A. R. Lyon, S. E. Harding and J. Gorelik (2014). "Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling." J Mol Cell Cardiol, 67: 38-48.
Trayanova N. A. and P. M. Boyle (2014). "Advances in modeling ventricular arrhythmias: from mechanisms to the clinic." Wiley Interdiscip Rev Syst Biol Med, 6(2): 209-24.