Publications

Tanskanen, A. J., Greenstein, J. L., Chen, M., Sun, S. X. and Winslow, R. L. (2007). Protein geometry and placement in the cardiac dyad influence macroscopic properties of calcium-induced calcium release. Biophys. J., 92: 3379-3396.

Cortassa S., M. A. Aon, B. O'Rourke, R. Jacques, H. J. Tseng, E. Marban, R. L. Winslow (2006). "A computational model integrating electrophysiology, contraction and mitochondrial bioenergetics in the ventricular myocyte." Biophys J., 91(4): 1564-1589.

Winslow, R. L. Tanskanen, A., M. Chen and Greenstein, J. L. (2006). Multi-scale models of calcium signaling in the cardiac dyad. In: Interactive and Integrative Cardiology, Ann. NY Acad. Sci. Biophys. J., 1080: 362-375, Edts. S. Sideman, R Beyar and A Landsberg.

Tanskanen, A. and Winslow, R. L. (2006). Integrative Structurally-detailed model of calcium dynamics in the cardiac diad. SIAM Journal of Multi-Scale Modeling and Simulation, 5(4): 1280-1296. 

Greenstein, J. L., Hinch, R., and Winslow, R. L. (2006). Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte. Biophys. J., 90(1): 77-91.

Hinch, R., Greenstein, J. L. and Winslow, R. L. (2006). Multi-scale models of local control of calcium induced calcium release. Prog. Biophys. Mol Biol., 90(1-3): 136-150.

Winslow R. L., S. Cortassa, J. L. Greenstein (2005). "Using Models of the Myocyte for Functional Interpretation of Cardiac Proteomic Data." J. Physiol., 563(1): 73-81.

Cortassa S., M. A. Aon, R. L. Winslow, B. O'Rourke (2004). "A mitochondrial oscillator dependent on reactive oxygen species." Biophys J., 87(3): 2060-2073.

Hinch, R., Greenstein, J. L., Tanskanen, A. J., Xu, L. and Winslow, R. L. (2004). A simplified local control model of calcium-induced calcium release in cardiac ventricular myocytes. Biophys. J., 87: 3723-3736.  

Cortassa S., M. A. Aon, E. Marban, R. L. Winslow, B. O'Rourke (2002). "An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics." Biophys J., 84(4): 2734-2755. 

Greenstein, J. L. and Winslow, R. L. (2002). An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release. Biophys. J., 83(6): 2918-2945.

Winslow, R. L. Greenstein, J., Tomaselli, G. F., and ORourke, B. (2000). Computational models of the failing myocyte: relating altered gene expression to cellular function. Phil. Trans. Roy. Soc. A, 359(1783): 1187-1200.

Winslow, R. L., Rice, J. J., Jafri, S., Marban, E., and ORourke, B. (1999). Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure II: Model Studies. Circ. Res., 84: 571-586.

Jafri, M. S., Rice, J. J., and Winslow, R. L. (1998). Cardiac Ca2+ dynamics: the roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophys. J., 74(3): 1149-1168.