Nicholas J. Schork, Scripps/UCSD, “Enabling Genomic and Individualized Medicine: Strategies and Challenges”

March 26, 2013 @ 9:00 am – 10:00 am

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“Enabling Genomic and Individualized Medicine: Strategies and Challenges”

Nicholas J. Schork, Ph.D., is Professor, Molecular and Experimental Medicine, at The Scripps Research Institute (TSRI) and Director of Bioinformatics and Biostatistics at the Scripps Translational Science Institute (STSI). Dr. Schork has published over 400 articles in the area of the genetic dissection of complex phenotypes. These publications include both methodological and applied studies. Dr. Schork has a long history of providing biostatistical and bioinformatics oversight and support to large consortium efforts such as the NHLBI-funded Family Blood Pressure Program, the NIA-funded Longevity Consortium, and the NIMH-funded Bipolar Genetics Consortium. Dr. Schork received his Ph.D. from the University of Michigan in 1994. He was a faculty member in the Department of Genetics at Case Western Reserve University from 1994-2001, and a Professor in the Departments of Psychiatry and Family and Preventive Medicine (Biostatistics) at UCSD from 2001-2007 before joining Scripps.


“Enabling Genomic and Individualized Medicine: Strategies and Challenges”

There has been considerable interest and hype surrounding the concepts of “genomic” and “individualized” medicine; i.e., the belief that it will be possible to identify optimal therapeutic and preventive interventions for an individual patient based on that patient’s unique genomic and pathophysiologic profile. However, developing routine clinical protocols for enabling genomic and individualized medicine is not trivial. In this talk, I describe some research strategies focused on the delivery of genomic and individualized medicine, including tumor genomic profiling for cancer therapeutic matching, individual patient-oriented research studies, and n-of-1 clinical trials. The goal of these research strategies is to simultaneously actualize genomic and individualized medicine with true objective and scientific backing as well as expose problem areas and obtain insights that will benefit future patients.


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