ICM establishes ITCR Computational Medicine Core
Date: September 19, 2014
The Institute for Computational Medicine (ICM) is pleased to announce the establishment of a Computational Medicine Core. This new core, supported by NIH funding to the Institute for Clinical and Translational Research, will help faculty across the Johns Hopkins enterprise add computational modeling to their research endeavors.
The Computational Medicine Core was created to support innovative biomedical research programs at Johns Hopkins University. It offers services and consulting for investigators interested in mathematical modeling of complex biological systems in health and disease. Models may be used to achieve quantitative understanding of and to generate hypotheses about disease mechanisms and treatments that can then be tested in the laboratory and/or clinic.
For more information, Click Here.
Iraj Hosseini receives a 2015 Siebel Scholarship
Date: September 12, 2014
Iraj Hosseini, a Graduate Student in the lab of Feilim Mac Gabhann, Assistant Professor in the Department of Biomedical Engineering and Institute for Computational Medicine Core Faculty Member, has been awarded a 2015 Siebel Scholarship. Iraj received his M.Sc. and B.Sc. (with honors) from University of Alberta and Isfahan University, respectively. At JHU, Iraj has developed molecular-detailed multi-scale computational models of HIV infection to better understand HIV pathogenesis and design stem cell-based anti-HIV therapies. Iraj has co-authored over twenty peer reviewed journal articles and conference papers and received numerous awards including four international awards in RoboCup competitions, Alberta Ingenuity award, iCORE scholarship, Drescher scholarship and the Ruth Aranow fellowship in Computational Medicine. Beyond his academic achievements, Iraj leads novel efforts to reinvigorate PhD education and prepare students for alternative career opportunities. Iraj co-founded BME EDGE, obtaining $150,000 in competitive funding from the Provost's Office and matching funds from the BME department. At EDGE, Iraj co-chaired a team of 17 students and staff members to develop an integrated career pathway for graduate students through internships, professional development workshops, alumni speaker series, networking events and PhD-focused job fairs.
"The Siebel Scholars program was established in 2000 by the Siebel Foundation through grants to 17 of the most prestigious business, bioengineering, and computer science graduate programs. Each year, up to five graduate students from each partner institution are selected as Siebel Scholars to receive a $35,000 award for their final year of studies and join the vibrant community of leaders who collaborate, communicate, and institute meaningful change." Click here to read the full announcement on the Siebel Scholars Website.
Congratulations Iraj on your award!
Brian Lee awarded 2014-2015 David C. Gakenheimer Fellowship award
Date: September 8, 2014
Brian Lee, a second year BME Predoctoral Student in the lab of Dr. Michael Miller, Herschel and Ruth Seder Professor of Biomedical Engineering at Johns Hopkins, director of the university’s Center for Imaging Science, and core faculty member in the Institute for Computational Medicine, has been selected as the recipient of the Institute for Computational Medicine’s David C. Gakenheimer Fellowship, for the 2014-2015 academic year.
Dr. Gakenheimer, who holds a bachelor’s degree in engineering mechanics from Johns Hopkins University, generously funded this fellowship to provide support to a student conducting heart research in developing and advancing diagnostic methods such as detection, classification and treatment of rhythm disorders.
Congratulations Brian and good luck with your research!
Dr. Natalia Trayanova gives keynote lecture at 2014 SIAM Annual Meeting
Date: July 23, 2014
Natalia A. Trayanova, Murray B. Sachs Professor of Biomedical Engineering and the Institute for Computational Medicine, presented a keynote lecture at the 2014 SIAM Annual Conference of the Society for Industrial and Applied Mathematics. The conference was held July 7-11 in Chicago, Illinois. Natalia's presentation entitled “Virtual Electrophysiology Laboratory” was scheduled for Thurs, July 10.
Click here to view more information about the SIAM conference.
To view the abstract from Dr. Trayanova's presentation, click here.
Daniel Tward awarded at 2014 XSEDE Conference for best "lightning talk"
Date: July 21, 2014
BME PhD student Daniel Tward attended the 2014 Extreme Science and Engineering Discovery Environment (XSEDE) conference in Atlanta, Georgia and received a prize for the best "Lightning Talk". His presentation "Computational Anatomy Gateway: Leveraging XSEDE Computational Resources for Shape Analysis" was authored with Saurabh Jain, David Lee, Anthony Kolasny, Timothy Brown, Tilak Ratnanather, Laurent Younes and Michael Miller.
Computational Anatomy (CA) is a discipline focused on the quantitative analysis of the variability in biological shape. The Large Deformation Diffeomorphic Metric Mapping (LDDMM) is the key algorithm which assigns computable descriptors of anatomical shapes and a metric distance between shapes. This is achieved by describing populations of anatomical shapes as a group of diffeomorphic transformations applied to a template, and using a metric on the space of diffeomorphisms. LDDMM is being used extensively in the neuroimaging (www.mristudio.org) and cardiovascular imaging (www.cvrgrid.org) communities. There are two major components involved in shape analysis using this paradigm. First is the estimation of the template, and second is calculating the diffeomorphisms mapping the template to each subject in the population. Template estimation is a computationally expensive problem, which involves an iterative process, where each iteration calculates one diffeomorphism for each target. These can be calculated in parallel and independently of each other, and XSEDE is providing the resources, in particular those provided by the cluster Stampede, that make these computations for large populations possible. Mappings from the estimated template to each subject can also be run in parallel. In addition, the use of NVIDIA Tesla GPUs available on Stampede present the possibility of speeding up certain convolution-like calculations which lend themselves well to the General Purpose GPU computation model. We are also exploring the use of the available Xeon Phi Co-processors to increase the efficiency of our codes. This will have a huge impact on both the neuroimaging and cardiac imaging communities as we bring these shape analysis tools online for use by these communities through our webservice (www.mricloud.org), with the XSEDE Computational Anatomy Gateway providing the resources to handle the computational demands for large populations.
To view other lightning talks and link to more information about the XSEDE conference, visit their site at http://conferences.xsede.org/lightning-talks.
Student work overseen by Dr. Tilak Ratnanather featured in WSE Summer News
Date: June 17, 2014
An article in the Summer 2014 issue of JHU Engineering Magazine highlights a promising iPad app designed by Hopkins undergrads to help train deaf adults with cochlear implants (CI) to understand speech from the electrical signals that CI devices provide. Student team members include Margo Heston, Rohit Bhattacharya, and Joanne Song, all of the Department of Biomedical Engineering. Their work is overseen by Dr. Tilak Ratnanather, an associate research professor in the Center for Imaging Science and ICM core faculty member.
According to Heston, the app – named Speech Banana after the term specialists use to describe the area where all human speech appears on an audiogram – is not intended to replace traditional in-person auditory training, “But we want to supplement it.”
To read the entire article, click here.
Prof. René Vidal elected to the 2014 Class of IEEE Fellows
Date: June 13, 2014
Dr. René Vidal receives award in Florence, Italy
René Vidal has been named to the 2014 class of IEEE Computer Society Fellows. The IEEE Grade of Fellow recognizes unusual distinction in the profession and is conferred by the IEEE Board of Directors upon a person of outstanding and extraordinary qualifications and experience in IEEE-designated fields, and who has made important individual contributions to one or more of these fields. Dr. Vidal has been recognized for contributions to subspace clustering and motion segmentation in computer vision. He was presented with the award at the IEEE International Conference on Acoustics, Speech and Signal Processing in Florence, Italy, on Tuesday, May 6, 2014.
Dr. Vidal is an Associate Professor in the Department of Biomedical Engineering of Johns Hopkins University, with joint appointments in Computer Science, Electrical and Computer Engineering, and Mechanical Engineering. He is the director of the Vision Dynamics and Learning Lab, and a faculty member in the Center for Imaging Science (CIS), the Institute for Computational Medicine (ICM), and the Laboratory for Computational Sensing and Robotics (LCSR). For more information on his research, please see http://www.vision.jhu.edu.
ICM teams with CS on successful IDIES Seed Funding proposal
Date: June 10, 2014
The Johns Hopkins Institute for Data Intensive Engineering and Science (IDIES) Seed Funding Program has announced that the proposal "SIRENIC: Stream Infrastructure for the Real-time Analysis of Intensive Care Unit Sensor Data" by Yanif Ahmad and Yair Amir, both of the Department of Computer Science, and Raimond Winslow of the Department Biomedical Engineering and Institute for Computational Medicine, is among those selected for the first 2014 round of competitive awards. The goals of the IDIES seed funding initiative, which provides $25,000 to each recipient team, are to support data-intensive computing projects that involve areas relevant to IDIES and JHU institutional research priorities, are multidisciplinary, and build ideas and teams with good prospects for successful external research funding.
The goal of the SIRENIC project is to design and deploy an open-source data management framework as infrastructure for the real-time analysis of streaming patient physiological data in the intensive care unit (ICU) setting. The proposal aims at delivering a proof-of-concept data collection and analysis pipeline to support exploratory research activities in ICU healthcare, with the explicit capability to operate on live data and to empower alarms research and event detection in the real-time setting. The project brings together biomedical and computer science researchers with the capabilities to: i) instrument and capture patient physiology data with bedside sensor deployments in a Hopkins ICU, and ii) design a research-oriented stream analytics framework to assist medical and clinical researchers and practitioners in model development for rapidly evolving diseases with critical effects on patient health. Example diseases that exhibit both a rapid onset and evolution include infections such as sepsis, arrhythmias, seizures, pulmonary embolism, cardiogenic shock, and respiratory failure. Sepsis alone accounts for more than 200,000 deaths in the U.S. annually.
To read the full announcement on the JHU HUB website, click here.
Click here to read more about the IDIES Seed Funding Program on the IDIES website.
Sri Sarma appears on Today to promote Brain Games
Date: May 29, 2014
Dr. Sridevi Sarma, Assistant Professor of Biomedical Engineering and ICM core faculty member, guested on The Today Show with Kathy Lee & Hoda on Tuesday, May 27 in a segment promoting the National Geographic Channel series, Brain Games. Brain Games is a science entertainment television program that explores the components of the human brain. Episodes of Brain Games season 3 featuring Dr. Sarma will begin airing in July 2014. A video of Dr. Sarma’s appearance on The Today Show can be viewed below or here.
Clips of Dr. Sarma’s online episodes of Brain Games can be found here. Watch for Brain Games season 3 airing in July for additional episodes.
Medical Device Daily Features Research by Dr. Natalia Trayanova
Date: May 23, 2014
Research by Dr. Natalia Trayanova, Murray B. Sachs Professor of Biomedical Engineering and member of the Institute for Computational Medicine, was featured in the May 12 edition of Medical Device Daily. The story by Mark McCarty highlights her presentation at this year’s Heart Rhythm Society. From the story: "[Dr. Trayanova] remarked at the HRS session that the MRI effort in her lab is aimed at development of a multi-scale modeling platform, one possible use of which is to map out the optimal targets for ablation for ventricular tachycardia with a degree of precision she suggested is not currently available in clinical practice."
For more information about Dr. Trayanova’s presentation and for a link to the article,click here.