Computational Medicine Night is the Institute for Computational Medicine’s annual networking event geared towards undergraduates who are interested in learning about the academic discipline of Computational Medicine and the research conducted in ICM labs. Held each spring term, Computational Medicine Night showcases undergraduate research and provides a forum for interested students to meet and mingle with ICM faculty, students, and postdoctoral fellows, to gather information about the Computational Medicine Minor, and to ask questions.
Computational Medicine Night includes:
Overview of the Computational Medicine Minor
Joel Bader, PhD
Director, Institute for Computational Medicine
Undergraduate Research Presentations
(sample presentation abstract):
Using Computational Cardiac Models to Simulate Delivery of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (hiPSC CM)
William Franceschi, 2nd year Biomedical Engineering student, Trayanova Lab
HiPSCs are generated from somatic cells and can be differentiated into various kinds of human tissue. HiPSCs are commonly used in drug testing and modeling genetic diseases of organs. Due to their ability to differentiate into many kinds of tissue, patient specific hiPSCs have great potential in treating diseased organs by regenerating healthy tissue. Currently, hiPSC CMs cannot be fully differentiated. Thus, these immature hiPSC CMs have different electrophysiological properties than native CMs. Previous attempts to treat cardiac diseases by injecting hiPSC CMs often result in arrhythmia. The arrhythmogenic mechanisms remain unclear. The goal of this study was to simulate intramyocardial injection of hiPSC CMs into a heart after myocardial infarction heart failure and reveal conditions that can lead to arrhythmia.
Eat, Meet, Mingle
Mingle with faculty, students and postdoctoral fellows, view posters, and enjoy dinner while you’re at it!